Optimization of an accelerator-based epithermal neutron source for neutron capture therapy
نویسندگان
چکیده
منابع مشابه
Optimization of an accelerator-based epithermal neutron source for neutron capture therapy.
A modeling investigation was performed to choose moderator material and size for creating optimal epithermal neutron beams for BNCT based on a proton accelerator and the (7)Li(p,n)(7)Be reaction as a neutrons source. An optimal configuration is suggested for the beam shaping assembly made from polytetrafluoroethylene and magnesium fluorine to be placed on high current IPPE proton accelerator KG...
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Nowadays neutron capture therapy looks very promising method of cancer treatment, especially for brain tumors by reason of selective damage cancer cells. Treatment effect of this method based on neutrons nuclear reaction with nuclides B, Gd. These nuclides have high cross-section of interaction with thermal neutrons. Unfortunately, thermal neutrons could enter only in near surface tissue and co...
متن کاملDesign of an accelerator-based neutron source for neutron capture therapy.
The boron neutron capture therapy is mainly suited in the treatment of some tumor kinds which revealed ineffective to the traditional radiotherapy. In order to take advantage of such a therapeutic modality in hospital environments, neutron beams of suitable energy and flux levels provided by compact size facilities are needed. The advantages and drawbacks of several neutron beams are here analy...
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Pilot innovative accelerator based neutron source for neutron capture therapy of cancer [1] is now on the threshold of its operation at the BINP, Russia. One of the main elements of the facility is lithium target producing neutrons via threshold Li(p,n)Be reaction at 25 kW proton beam with energies 1.915 MeV or 2.5 MeV. In the present report, choice of target is substantiated, the main problems...
متن کاملAn Epithermal Neutron Source for BNCT Based on an ESQ - Accelerator
An accelerator-based BNCT facility is under development at the Lawrence Berkeley National Laboratory. Neutrons will be produced via the 7Li(p,n) reaction at proton energies of about 2.5 MeV with subsequent moderation and filtering for shaping epithermal neutron beams for BNCT. Moderator, filter, and shielding assemblies have been modeled using MCNP. Head-phantom dose distributions have been cal...
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ژورنال
عنوان ژورنال: Applied Radiation and Isotopes
سال: 2004
ISSN: 0969-8043
DOI: 10.1016/j.apradiso.2004.05.028